abstract：:Purpose: The aim of this study was to investigate the relationship between stressful life events and sleep quality and to probe the role of rumination and resilience in the relationship. Method: The Adolescent Self-Rating Life Events Checklist, Ruminative Responses Scale, Connor-Davidson Resilience Scale, and Pittsbur...

journal_title：Frontiers in psychiatry

authors： Li Y,Gu S,Wang Z,Li H,Xu X,Zhu H,Deng S,Ma X,Feng G,Wang F,Huang JH

更新日期：2019-05-27 00:00:00

abstract：:Background: Mental disorders are highly prevalent among university students. Distance-learning students are particularly burdened and have limited access to conventional university health services. Interventions for stress are sought after in distance learners and may help increase treatment coverage. Internet-based i...

journal_title：Frontiers in psychiatry

authors： Harrer M,Apolinário-Hagen J,Fritsche L,Drüge M,Krings L,Beck K,Salewski C,Zarski AC,Lehr D,Baumeister H,Ebert DD

更新日期：2019-05-21 00:00:00

abstract：:Attention deficit hyperactivity disorder (ADHD) is a disorder most frequently diagnosed in children and adolescents. Although ADHD can be effectively treated with psychostimulants, a significant proportion of patients discontinue treatment because of adverse events or insufficient improvement of symptoms. In addition,...

journal_title：Frontiers in psychiatry

authors： Sierawska A,Prehn-Kristensen A,Moliadze V,Krauel K,Nowak R,Freitag CM,Siniatchkin M,Buyx A

更新日期：2019-05-16 00:00:00

abstract：:Acute growth in negative affect is thought to play a major role in triggering relapse in opiate-dependent individuals. Consistent with this view, three lab studies have demonstrated that negative mood induction increases opiate craving in opiate-dependent individuals. The current study sought to confirm these effects ...

journal_title：Frontiers in psychiatry

authors： Hogarth L,Hardy L,Bakou A,Mahlberg J,Weidemann G,Cashel S,Moustafa AA

更新日期：2019-05-15 00:00:00

abstract：:The issues that confront families when a parent experiences mental illness are complex. This often means that multiple service systems must be engaged to meet families' needs, including those related to intergenerational experiences of mental health and illness. A multisystem approach to public mental health care is w...

journal_title：Frontiers in psychiatry

authors： Isobel S,Allchin B,Goodyear M,Gladstone BM

更新日期：2019-05-08 00:00:00

abstract：:This study examined parental recognition of bullying victimization and associated factors among evacuated children after the 2011 Fukushima Daiichi Nuclear Power Plant accident, using a 3-year follow-up data (wave 1: January 2012; wave 2: January 2013; wave 3: February 2014). The sample included the caregivers of 2,61...

journal_title：Frontiers in psychiatry

authors： Oe M,Maeda M,Ohira T,Itagaki S,Harigane M,Suzuki Y,Yabe H,Yasumura S,Kamiya K,Ohto H

更新日期：2019-05-03 00:00:00

abstract：:Adenosine-to-inosine (A-to-I) RNA editing is a co-/posttranscriptional modification of double-stranded RNA, catalyzed by the adenosine deaminase acting on RNA (ADAR) family of enzymes, which results in recognition of inosine as guanosine by translational and splicing machinery causing potential recoding events in amin...

journal_title：Frontiers in psychiatry

authors： Dick ALW,Khermesh K,Paul E,Stamp F,Levanon EY,Chen A

更新日期：2019-04-26 00:00:00

abstract：:Background: Children of parents with a mental illness (COPMI) are more likely to experience negative long-term adversities. However, interventions to support their needs early can significantly enhance adjustment and reduce negative outcomes. Approximately one in four children currently lives with a parent with mental...

journal_title：Frontiers in psychiatry

authors： Christiansen H,Bauer A,Fatima B,Goodyear M,Lund IO,Zechmeister-Koss I,Paul JL

更新日期：2019-04-17 00:00:00

abstract：:This study compares the impact of repeated injections of baclofen (an agonist of GABAB receptors) or diazepam (a benzodiazepine having an agonist action on GABAA receptors) given during the alcohol-withdrawal period on the stress-induced restoration of alcohol-seeking behavior and hypothalamic-pituitary-adrenal (HPA) ...

journal_title：Frontiers in psychiatry

authors： Rabat Y,Henkous N,Corio M,Nogues X,Beracochea D

更新日期：2019-04-16 00:00:00

abstract：:Down syndrome (DS) is associated with intellectual disability and an ultra-high risk of developing dementia. Informant ratings are invaluable to assess abilities and related changes in adults with DS, particularly for those with more severe intellectual disabilities and/or cognitive decline. We previously developed th...

journal_title：Frontiers in psychiatry

authors： Startin CM,Lowe B,Hamburg S,Hithersay R,Strydom A,LonDownS Consortium.

更新日期：2019-04-16 00:00:00

abstract：:Previous studies have reported an association between verbal abuse in early childhood and structural and functional alterations in the young adult brain, supporting the existence of critical periods in human brain development. In addition, exposure to verbal abuse in early childhood is strongly correlated with lifetim...

journal_title：Frontiers in psychiatry

authors： Shin DW,Yoon T,Jeong B

更新日期：2019-04-16 00:00:00

abstract：:Background: Voxel-based morphometry studies have repeatedly highlighted the presence of distributed gray matter changes in schizophrenia, but to date, it is not clear if clinically useful prognostic information can be gleaned from structural imaging. The suspected association between gray matter volume (GMV) and durat...

journal_title：Frontiers in psychiatry

authors： Li M,Li X,Das TK,Deng W,Li Y,Zhao L,Ma X,Wang Y,Yu H,Meng Y,Wang Q,Palaniyappan L,Li T

更新日期：2019-04-15 00:00:00

abstract：:Background: Catatonic phenomena such as stupor, mutism, stereotypy, echolalia, echopraxia, affective flattening, psychomotor deficits, and social withdrawal are characteristic symptoms of both schizophrenia and autism spectrum disorders (ASD), suggesting overlapping pathophysiological similarities such as altered glut...

journal_title：Frontiers in psychiatry

authors： Hefter D,Topor CE,Gass P,Hirjak D

更新日期：2019-04-12 00:00:00

abstract：:Aim: With the introduction of "Electronic Medical Record" (EMR) a wealth of digital data has become available. This provides a unique opportunity for exploring precedents for seclusion. This study explored the feasibility of text mining analysis in the EMR to eventually help reduce the use of seclusion in psychiatry. ...

journal_title：Frontiers in psychiatry

authors： Hazewinkel MC,de Winter RFP,van Est RW,van Hyfte D,Wijnschenk D,Miedema N,Hoencamp E

更新日期：2019-04-11 00:00:00

abstract：:The most replicated neuroanatomical finding in autism is the tendency toward brain overgrowth, especially in younger children. Research shows that both gray and white matter are enlarged. Proposed mechanisms underlying brain enlargement include abnormal inflammatory and neurotrophic signals that lead to excessive, abe...

journal_title：Frontiers in psychiatry

authors： Sokol DK,Maloney B,Westmark CJ,Lahiri DK

更新日期：2019-04-10 00:00:00

abstract：:The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms t...

journal_title：Frontiers in psychiatry

authors： Kelly RR,McDonald LT,Jensen NR,Sidles SJ,LaRue AC

更新日期：2019-04-09 00:00:00

abstract：:Introduction: Vitamin D inadequacy or deficiency (VDID) has been reported in a high percentage of otherwise healthy individuals. Factors that may contribute to the high prevalence of VDID in people with mental disorders include diet low in vitamin D, poor sunlight exposure, decrease in cutaneous vitamin D synthesis, i...

journal_title：Frontiers in psychiatry

authors： Cuomo A,Maina G,Bolognesi S,Rosso G,Beccarini Crescenzi B,Zanobini F,Goracci A,Facchi E,Favaretto E,Baldini I,Santucci A,Fagiolini A

更新日期：2019-03-29 00:00:00

abstract：:The gut hormone ghrelin has been implicated in a variety of functional roles in the central nervous system through the brain-gut axis, one of which is an anti-inflammatory effect. An aberrant brain-gut axis producing immune dysfunction has been implicated in the pathobiology of autism spectrum disorder (ASD), and elev...

journal_title：Frontiers in psychiatry

authors： Yamashita Y,Makinodan M,Toritsuka M,Yamauchi T,Ikawa D,Kimoto S,Komori T,Takada R,Kayashima Y,Hamano-Iwasa K,Tsujii M,Matsuzaki H,Kishimoto T

更新日期：2019-03-26 00:00:00

abstract：:Background: Approach and avoidance motivation have been thoroughly studied in common mental disorders, which are prevalent in the military context. Approach/avoidance motivational dispositions underlie emotion responses and are thought to influence emotion dysregulation. However, studies on the mediating role of emoti...

journal_title：Frontiers in psychiatry

authors： Wang X,Zhang R,Chen X,Liu K,Wang L,Zhang J,Liu X,Feng Z

更新日期：2019-03-22 00:00:00

abstract：:Translational research aiming to elucidate mediators and moderators of placebo and nocebo effects is highly relevant. This experimental study tested effects of a brief progressive muscle relaxation (PMR) exercise, designed to alter psychobiological stress parameters, on the magnitude of placebo and nocebo effects in a...

journal_title：Frontiers in psychiatry

authors： Elsenbruch S,Roderigo T,Enck P,Benson S

更新日期：2019-03-21 00:00:00

abstract：:Generalized anxiety disorder (GAD) is a common but serious form of anxiety disorder. Despite this, the rate of GAD recognition in primary care remains low in both Western and Eastern countries. The GAD-7 and GAD-2 were developed to efficiently identify people with GAD, and their reliability and validity have been well...

journal_title：Frontiers in psychiatry

authors： Ahn JK,Kim Y,Choi KH

更新日期：2019-03-18 00:00:00

abstract：:Background: Primary indicated prevention in individuals at-risk for psychosis has the potential to improve the outcomes of this disorder. The ability to detect the majority of at-risk individuals is the main barrier toward extending benefits for the lives of many adolescents and young adults. Current detection strateg...

journal_title：Frontiers in psychiatry

authors： Fusar-Poli P,Oliver D,Spada G,Patel R,Stewart R,Dobson R,McGuire P

更新日期：2019-03-13 00:00:00

abstract：:The dark triad (DT) traits-psychopathy, narcissism and Machiavellianism-have collectively been linked to reduced empathy and increased aggression; however, their association with distinct empathic subtypes remains unclear; and unique links to indirect relational aggression (IRA) have not been delineated. Moreover, whe...

journal_title：Frontiers in psychiatry

authors： Heym N,Firth J,Kibowski F,Sumich A,Egan V,Bloxsom CAJ

更新日期：2019-03-12 00:00:00

abstract：:Background: People with severe mental disorders (SMDs) have higher disease and death rates than the general population. Stigma (negative attitudes and perceptions) contributes to limited access to health services and a lower quality of medical assistance in this population, and it is manifested as negative attitudes, ...

journal_title：Frontiers in psychiatry

authors： Grandón P,Saldivia S,Vaccari P,Ramirez-Vielma R,Victoriano V,Zambrano C,Ortiz C,Cova F

更新日期：2019-03-07 00:00:00

abstract：:Background: Recent models of eating disorders (EDs) have proposed social and emotional difficulties as key factors in the development and maintenance of the illness. While a number of studies have demonstrated difficulties in theory of mind and emotion recognition, little is known about empathic abilities in those wit...

journal_title：Frontiers in psychiatry

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2019-03-04 00:00:00

abstract：:Substance use disorders are chronic, relapsing, and harmful conditions characterized by executive dysfunction. While there are currently no approved pharmacotherapy options for stimulant and cannabis use disorders, there are several evidence-based options available to help reduce symptoms during detoxification and aid...

journal_title：Frontiers in psychiatry

authors： Butler K,Le Foll B

更新日期：2019-03-01 00:00:00

abstract：:Major depressive disorder (MDD) is a very common stress-related mental disorder that carries a huge burden for affected patients and the society. It is associated with a high mortality that derives from suicidality and the development of serious medical conditions such as heart diseases, diabetes, and stroke. Although...

journal_title：Frontiers in psychiatry

authors： Menke A

更新日期：2019-02-28 00:00:00

abstract：:Background: Catatonia is a syndrome comprising psychomotor, behavioral, and autonomous symptoms which may occur in the context of severe schizophrenic, affective, and other mental disorders or medical conditions. Treatment options include high dose benzodiazepines (lorazepam) and electroconvulsive therapy (ECT) with s...

journal_title：Frontiers in psychiatry

authors： Zilles D

更新日期：2019-02-27 00:00:00

abstract：:Objective: The purpose of this study was to investigate the influence of parenting style on children's behavior problems after the Great East Japan Earthquake in 2011. Methods: Participants were children exposed to the 2011 disaster at preschool age (n = 163). Data were collected from August 2012 to March 2013, and fr...

journal_title：Frontiers in psychiatry

authors： Miki T,Fujiwara T,Yagi J,Homma H,Mashiko H,Nagao K,Okuyama M

更新日期：2019-02-19 00:00:00

abstract：:Despite many studies documenting the prevalence of various co-occurring psychiatric symptoms in children and adults with ASD, less is known about how these symptoms relate to subtypes defined by particular phenotypic features within the ASD population. We examined the severity and prevalence of comorbid symptoms of ps...

journal_title：Frontiers in psychiatry

authors： Plesa Skwerer D,Joseph RM,Eggleston B,Meyer SR,Tager-Flusberg H

更新日期：2019-02-18 00:00:00

abstract：:Background: Recently, many case-control studies have reported the association between 5-HTTLPR polymorphism and autism risk. However, the results are inconclusive and conflicting. To investigate the genetic association of 5-HTTLPR polymorphism and autism risk, we conducted a comprehensive meta-analysis based on previo...

journal_title：Frontiers in psychiatry

authors： Wang H,Yin F,Gao J,Fan X

更新日期：2019-02-13 00:00:00

abstract：:In depression, brain and behavioral correlates of decision-making differ between individuals with and without suicidal thoughts and behaviors. Though promising, it remains unknown if these potential biomarkers of suicidality will generalize to other high-risk clinical populations. To preliminarily assess whether brain...

journal_title：Frontiers in psychiatry

authors： Barredo J,Aiken E,van 't Wout-Frank M,Greenberg BD,Carpenter LL,Philip NS

更新日期：2019-02-12 00:00:00

abstract：:Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have exa...

journal_title：Frontiers in psychiatry

authors： Cheung SG,Goldenthal AR,Uhlemann AC,Mann JJ,Miller JM,Sublette ME

更新日期：2019-02-11 00:00:00

abstract：:Background: Left-behind children (LBC) are becoming a widespread phenomenon and face higher risks of psychological and educational problems. Our study aimed to explore school bullying in LBC and examine the effectiveness of art therapy intervention for reducing bullying victimization affecting LBC in rural areas. Meth...

journal_title：Frontiers in psychiatry

authors： Yan H,Chen J,Huang J

更新日期：2019-02-07 00:00:00

abstract：:Sleep is a quiescent behavioral state during which complex homeostatic functions essential to health and well-being occur. Insomnia is a very common psychiatric disorder leading to a myriad of detrimental effects including loss of concentration, memory, and performance as well as disease. Current pharmaceutical treatm...

journal_title：Frontiers in psychiatry

authors： Jerath R,Beveridge C,Barnes VA

更新日期：2019-01-29 00:00:00

abstract：:Excessive glutamate release has been linked to stress and many neurodegenerative diseases. Evidence indicates abnormalities of glutamatergic neurotransmission or glutamatergic dysfunction as playing an important role in the development of many major psychiatric disorders (e.g., schizophrenia, bipolar disorder, and maj...

journal_title：Frontiers in psychiatry

authors： Li CT,Yang KC,Lin WC

更新日期：2019-01-24 00:00:00

abstract：:Elevation of the blood ethanol concentration (BEC) to > 80 mg/dL (17.4 mM) after binge drinking enhances inflammation in brain and neuroimmune signaling pathways. Morphine abuse is frequently linked to excessive drinking. Morphine exerts its actions mainly via the seven transmembrane G-protein-coupled mu opioid recept...

journal_title：Frontiers in psychiatry

authors： Chang SL,Huang W,Han H,Sariyer IK

更新日期：2019-01-22 00:00:00

abstract：:With the opioid crisis in North America, opioid addiction has come in the spotlight and reveals the weakness of the current treatments. Two main opioid substitution therapies (OST) exist: buprenorphine and methadone. These two molecules are mu opioid receptor agonists but with different pharmacodynamic and pharmacokin...

journal_title：Frontiers in psychiatry

authors： Noble F,Marie N

更新日期：2019-01-18 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：:Objectives: This study aimed to examine the rate of remission in individuals experiencing early-onset poststroke depression (PSD) in China and to identify predictors of remission during a 3-month follow-up. This study also explored the interaction between cognitive impairment and depression. Methods: A total of 820 pa...

journal_title：Frontiers in psychiatry

authors： Huang J,Zhou FC,Guan B,Zhang N,Wang A,Yu P,Zhou L,Wang CY,Wang C

更新日期：2019-01-08 00:00:00